#Fragments of tubular adenoma serial

This study has uncovered a potential role for the use of additional serial sections in the morphological reappraisal of small hyperplastic polyps, especially when proximally located.ДЄlthough serrated polyps have in common a saw-tooth morphology of crypts, it is important to distinguish between hyperplastic polyps (HPs) and sessile serrated lesions (SSLs) because of the inherent difference in risk of malignant transformation. Histopathological distinction between hyperplastic polyps and sessile serrated lesions remains a challenge. An average of 3.6 serial sections were required for a change in diagnosis. They were all less than 5вЂ‰mm and represented 14.3% of proximal polyps and 10.4% of distal polyps. After 8 additional serial sections, 11 (10.7%) were reclassified as sessile serrated lesions. Of the 103 confirmed hyperplastic polyps, 7 (6.8%) were proximal, and 8 (7.8%) had a largest fragment size of в‰Ґ5вЂ‰mm andвЂ‰<вЂ‰10вЂ‰mm. Of an initial 147 hyperplastic polyps from 93 patients, 9 (6.1%) were classified as sessile serrated lesions, 103 as hyperplastic polyps, and 35 as other. Eight additional serial sections were performed for the confirmed hyperplastic polyp group and reviewed. The slides were reviewed and classified as hyperplastic polyps, sessile serrated lesion, or other, using current World Health Organization criteria. MethodsД¬linicopathological data for all colorectal hyperplastic polyps diagnosed in 20 was collected. Our aim was to reclassify previously diagnosed hyperplastic polyps as sessile serrated lesions or confirmed hyperplastic polyps, using additional serial sections. Sessile serrated lesions and hyperplastic polyps are types of serrated polyps which confer different malignancy risks, and surveillance intervals, and are sometimes difficult to discriminate. The histological discrimination of hyperplastic polyps from sessile serrated lesions can be difficult.